Acetyl L-Carnitine Arginate, 100 capsules

                                                        LE788
                            Acetyl-L-Carnitine Arginate 100 capsules

                                                         $44.25

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Acetyl-l-carnitine arginate is a patented form of carnitine that stimulates the growth of neurites in the brain. Studies show that acetyl-l-carnitine arginate stimulates the growth of new neurites by an astounding 19.5%, which is almost four times better than acetyl-l-carnitine.

The acetylated form of L-carnitine (acetyl-L-carnitine) facilitates the synthesis and release of acetylcholine by donating its acetyl group to be used in the production of acetylcholine, an important neurotransmitter. Acetyl-L-carnitine arginate acts together with acetyl-L-carnitine to increase neurite growth.₁Acetyl-L-carnitine also enhances the release of dopamine from neurons and helps it bind to dopamine receptors.* Numerous human and animal studies validate the multiple beneficial mechanisms that acetyl-L-carnitine exerts in the brain.

The amino acid acetyl-L-carnitine boosts mitochondrial energy production through its ability to facilitate fatty acid transport and oxidation in the cell.*

Since 1995, Life Extension members have been supplementing with acetyl-L-carnitine and deriving the many benefits this form of carnitine has shown in published studies. With the discovery of acetyl-L-carnitine arginate, the benefits of acetyl-L-carnitine can now be greatly augmented.

The acetylated ester of the amino acid acetyl-L-carnitine (ALC) plays a critical role in maintaining youthful cellular energy metabolism and blood flow.

Two major factors involved with brain aging are

Diminished brain cell metabolism
Reduced cerebral circulation.

ALC easily crosses the blood-brain barrier and its potential role in protecting neurological function is clear.

Studies show that ALC may prevent the neural impairment that normally occurs in oxygen deprivation and researchers have suggested that ALC should be given to children who suffer from oxygen deprivation in the womb. In published reports, short-term administration of ALC reversed ammonia-induced brain cell abnormalities and normalized brain cell energy metabolism in mice. The researchers suggested that the protective effect of acetyl-L-carnitine may maintain the energy-producing capabilities (mitochondrial respiration) of the central nervous system and emphasized its value for people with diseases that elevate ammonia levels in the blood, such as cirrhosis of the liver.

About 95% of cellular energy occurs in the mitochondria and diseases of aging are increasingly being referred to as “mitochondria disorders.” Acetyl-L-carnitine is the biologically active amino acid involved in the transport of fatty acids into the cell’s mitochondria for the purpose of producing energy.

Acetyl-L-carnitine is sold as an expensive drug in Europe to treat heart and neurological disease. It can increase muscle mass and convert body fat into energy. Acetyl-L-carnitine has been shown to protect brain cells against aging-related degeneration and improve mood, memory and cognition. People use acetyl-L-carnitine to maintain their immune competence and reduce the formation of the aging pigment lipofuscin. The most important effect of acetyl-L-carnitine, however, is to maintain the function of the cell’s energy powerhouse, the mitochondria. Published research continues to substantiate the multi-faceted benefits of this critical amino acid supplement.

Supplement Facts
Serving Size: 1 capsule Servings per container: 100
Amount per Serving
Acetyl-L-Carnitine Hydrochloride	300 mg
Acetyl-L-Carnitine Arginate Dihydrochloride	320 mg
Other ingredients: gelatin, magnesium stearate, rice flour.

Dosage and use:

Acetyl-L-carnitine may have a stimulating effect, therefore, it may be unwise to take it in the evening.
Two to four capsules daily are recommended for most people.
Acetyl-L-carnitine is most effectively utilized when taken on an empty stomach with water or juice, in divided dosages 30-45 minutes before breakfast and lunch.

Warnings

Keep out of reach of children.
Do not exceed recommended dose.
If you have a bad reaction to this product, discontinue use.
When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

If you are using it for Alzheimer’s or another serious disorder take one capsule on an empty stomach (30-45 minutes before meals or two to three hours after meals) every four hours unless your physician has recommended otherwise

References
1 Taglialatela G, Navarra D, Olivi A, et al, Neurite outgrowth in PC12 cells stimulated by acetyl-L-carnitine arginine amide. Neurochem Res 1995 Jan;20(1):1-9.

Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18.

This page was last modified on Tuesday September 02, 2008