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Super Ubiquinol CoQ10 50 mg. 100 softgels |
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LE1425 $43.50
Life Extension has consistently introduced more potent and better absorbed forms of coenzyme Q10 since the product first came on the market in the early 80s. The new Super Ubiquinol with Enhanced Mitochondrial Support™ contains an organic compound called Prima Vie® shilajit that research has shown to double levels of CoQ10 in the mitochondria.1 Shilajit has been shown to help restore and sustain cellular energy. The latest studies reveal that when shilajit is combined with CoQ10, cellular energy gains substantially increase. In a breakthrough preliminary study, the combination of CoQ10 and shilajit produced a 56% increase in cellular energy production in the brain—40% better than CoQ10 alone. In muscle there was a 144% increase, or 27% better than CoQ10 alone.2 Researchers have found that shilajit works to boost CoQ10’s beneficial effects by:
Scientific analysis shows that shilajit itself is rich in essential compounds that promote mitochondrial metabolism. Part of shilajit’s beneficial effects derives from its ability to help the mitochondria convert fats and sugars into adenosine triphosphate, or ATP—the body’s main source of energy.5-9 Combining ubiquinol CoQ10 with shilajit generates a powerful synergy that supports more youthful cellular energy production than CoQ10 alone.2,4,5 What’s more, Life Extension has added this novel ingredient to its CoQ10 formulations without increasing the price. More humans are supplementing with coenzyme Q10 than ever before. One reason is the increased awareness that the "statin" drugs used to lower LDL and cholesterol depletes the body of CoQ10. What most doctors don't know, however, is that normal aging may result in a greater reduction in CoQ10 than is caused by taking statin drugs. For example, while statin drugs have been shown to reduce plasma CoQ10 by 40%,10 the aging process reduces CoQ10 levels in the heart muscle wall by 72%.11 What is particularly frightening is the thought of people taking statin drugs who fail to supplement with CoQ10. The CoQ10 deficit caused by the dual affects of aging12 and statin drug use could result in severe depletion of cellular vitality.
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More Information on CoQ10
CoQ10 is required to convert fats and sugars into cellular energy, yet the natural production of CoQ10 declines with advancing age. When the body has an ample amount of CoQ10 the mitochondria can work most efficiently throughout the entire body, in cells everywhere, including the most densely populated area, the heart. Coenzyme Q10 is incorporated into the mitochondria of cells throughout the body where it facilitates and regulates the transformation of fats and sugars into energy. A large body of scientific evidence shows that CoQ10’s ability to restore mitochondrial function has a profound effect on one’s overall health. As people age, their natural synthesis of CoQ10 slowly declines. When people take “statin” cholesterol lowering drugs, CoQ10 synthesis can be reduced even further. With the availability of this highly absorbable coenzyme Q10, it becomes much more affordable to supplement with greater doses. For those seeking the higher doses now being recommended by more scientists, one of the new emulsified 30 mg capsules would provide an efficient and economic method of increasing blood levels of coenzyme Q10.
*Effect of Statin Drug on Coenzyme Q10 Plasma Levels In a study at Columbia University College of Physicians and Surgeons in New York, 45 subjects, including men and women, with elevated low-density lipoprotein (LDL) levels (thus at risk for cardiovascular disease) received 80 milligrams of oral atorvastatin for thirty days. After two weeks and at the study's conclusion, the participants were examined for changes in liver enzymes, kidney function and any adverse effects, including muscle pain or weakness. Plasma levels of coenzyme Q10 were measured at the beginning of the study, and at 14 and 30 days. In all participants, coenzyme Q10 levels were lower at both fourteen and thirty days than at the beginning of the study. Following two weeks of treatment with atorvastatin , plasma coenzyme Q10 levels in thirty-two participants were reduced by 49 percent. After thirty days, the mean coenzyme Q10 concentration was reduced from 1.26 micrograms per milliliter to 0.62 micrograms per milliliter. The findings could explain the most common adverse effects of statins, particularly muscle pain, exercise intolerance and myoglobinuria. The authors recommend that, “it may be reasonable to add coQ10 in patients receiving long-term treatment with statins in general, and atorvastatin in particular. This recommendation is strengthened by the general experience that oral coQ10—even in high doses—is well tolerated by patients.” ( Rundek T et al, “ Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke,” Arch Neur , vol 16, June 2004, p 884-92.) Printed with permission of Life Extension. For more information www.lef.org Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18. | ||||||||||||||||||||||||||
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This page was last modified on Friday December 30, 2011 |