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Super Ubiquinol CoQ10 50 mg. 100 softgels

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Super Ubiquinol with Mitochondrial Support 50 mg. 100 caps.

LE1425

Super Ubiquinol with Mitochondrial Support 50 mg. 100 softgels by Life Extension

$43.50

Add to Cart

 

Life Extension has consistently introduced more potent and better absorbed forms of coenzyme Q10 since the product first came on the market in the early 80s. The new Super Ubiquinol with Enhanced Mitochondrial Support™ contains an organic compound called Prima Vie® shilajit that research has shown to double levels of CoQ10 in the mitochondria.1

Shilajit has been shown to help restore and sustain cellular energy. The latest studies reveal that when shilajit is combined with CoQ10, cellular energy gains substantially increase.

In a breakthrough preliminary study, the combination of CoQ10 and shilajit produced a 56% increase in cellular energy production in the brain—40% better than CoQ10 alone. In muscle there was a 144% increase, or 27% better than CoQ10 alone.2

Researchers have found that shilajit works to boost CoQ10’s beneficial effects by:

  1. Stabilizing CoQ10 in its superior ubiquinol form, thereby prolonging its action at the cellular level.3,4
  2. Facilitating more efficient delivery of CoQ10 into the mitochondria, resulting in greater cellular energy output.5-9

Scientific analysis shows that shilajit itself is rich in essential compounds that promote mitochondrial metabolism. Part of shilajit’s beneficial effects derives from its ability to help the mitochondria convert fats and sugars into adenosine triphosphate, or ATP—the body’s main source of energy.5-9

Combining ubiquinol CoQ10 with shilajit generates a powerful synergy that supports more youthful cellular energy production than CoQ10 alone.2,4,5 What’s more, Life Extension has added this novel ingredient to its CoQ10 formulations without increasing the price.

More humans are supplementing with coenzyme Q10 than ever before. One reason is the increased awareness that the "statin" drugs used to lower LDL and cholesterol depletes the body of CoQ10. What most doctors don't know, however, is that normal aging may result in a greater reduction in CoQ10 than is caused by taking statin drugs. For example, while statin drugs have been shown to reduce plasma CoQ10 by 40%,10 the aging process reduces CoQ10 levels in the heart muscle wall by 72%.11 What is particularly frightening is the thought of people taking statin drugs who fail to supplement with CoQ10. The CoQ10 deficit caused by the dual affects of aging12 and statin drug use could result in severe depletion of cellular vitality.

 

Supplement Facts

Serving Size: 1 capsule
Servings per container: 100
Amount per Serving
Calories 3
     Calories from fat 3
Total fat 0.3 g
Ubiquinol (as Kaneka QH® Ubiquinol) 50 mg
PrimaVie® Shilajit fulvic acid complex 50 mg
Other ingredients:sunflower oil, gelatin, glycerin, purified water, yellow beeswax, caramel color.

Kaneka QH® is a registered trademark of Kaneka Corporation.
PrimaVie® is a registered trademark of Natreon, Inc.

Dosage and Use

  • Suggested dose is one to two softgel(s) daily for those over age 30.

  • For best utilization, take softgels with room temperature water after a meal.

Warnings

  • Keep out of reach of children.

  • Do not exceed recommended dose.

  • If you have a bad reaction to this product, discontinue use.

  • When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

 

References:
1. Systemic CoQ level in animals: Part II. Unpublished study. Natreon, Inc.; 2007.
2. Pharmacologyonline. 2009;1:817-25.
3. Pharmacologyonline. 2009;2:690-8.
4. Electronic Journal of Biotechnology. 2008 Jul 15;11(3).
5. Ghosal S. Shilajit in Perspective. Alpha Science International Limited; 2006.
6. Sci Total Environ. 1987 Apr;62:347-54.
7. Environ Sci Technol. 2002 Jul 15;36(14):3170-5.
8. Environ Sci Technol. 2002 May 1;36(9):1939-46.
9. Environ Sci Technol. 2009 Feb 1;43(3):878-83.
10. Ghirlanda G et al. J Clin Pharmacol. 1993 Mar;33(3):226-9.
11. Rosenfeldt FL et al. Biofactors. 1999;9(2-4):291-9.
12. Kalen A, Appelkvist E, Dallner G. Lipids and Aging. 1989; 24(7):579-84.

 

More Information on CoQ10

CoQ10 is required to convert fats and sugars into cellular energy, yet the natural production of CoQ10 declines  with advancing age. When the body has an ample amount of CoQ10 the mitochondria can work most efficiently throughout the entire body, in cells everywhere, including the most densely populated area, the heart.

Coenzyme Q10 is incorporated into the mitochondria of cells throughout the body where it facilitates and regulates the transformation of fats and sugars into energy. A large body of scientific evidence shows that CoQ10’s ability to restore mitochondrial function has a profound effect on one’s overall health.

As people age, their natural synthesis of CoQ10 slowly declines. When people take “statin” cholesterol lowering drugs, CoQ10 synthesis can be reduced even further.

With the availability of this highly absorbable coenzyme Q10, it becomes much more affordable to supplement with greater doses. For those seeking the higher doses now being recommended by more scientists, one of the new emulsified 30 mg capsules would provide an efficient and economic method of increasing blood levels of coenzyme Q10.

  • Coenzyme Q10 is an essential component of the respiratory cycle of the cell that takes place in the mitochondria and generates ATP, the cell’s energy currency.*
     
  • Orally administered CoQ10 goes directly to the mitochondria where it works to regulate the oxidation of fats and sugars into energy—an important function since the natural production of CoQ10 declines with advancing age. When the body has an ample amount of CoQ10 the mitochondria can work most efficiently throughout the entire body, in cells everywhere, including the most densely populated area, the heart.
     
  • Coenzyme Q10 has been shown to be effective against chronic inflammation of the arteries and heart muscle tissue resulting in cardiomyopathy.
     
  • Low blood levels of CoQ10 have been associated with immunodeficiency and/or an overactive active (allergic) immune system.
     

  • Helps prevent against a recurrence of heart attacks.
     
  • Plasma levels of CoQ10 are lowered with the use of statin drugs.*

*Effect of Statin Drug on Coenzyme Q10 Plasma Levels

In a study at Columbia University College of Physicians and Surgeons in New York, 45 subjects, including men and women,  with elevated low-density lipoprotein (LDL) levels (thus at risk for cardiovascular disease) received 80 milligrams of oral atorvastatin for thirty days. After two weeks and at the study's conclusion, the participants were examined for changes in liver enzymes, kidney function and any adverse effects, including muscle pain or weakness. Plasma levels of coenzyme Q10 were measured at the beginning of the study, and at 14 and 30 days.

In all participants, coenzyme Q10 levels were lower at both fourteen and thirty days than at the beginning of the study. Following two weeks of treatment with atorvastatin , plasma coenzyme Q10 levels in thirty-two participants were reduced by 49 percent. After thirty days, the mean coenzyme Q10 concentration was reduced from 1.26 micrograms per milliliter to 0.62 micrograms per milliliter.

The findings could explain the most common adverse effects of statins, particularly muscle pain, exercise intolerance and myoglobinuria. The authors recommend that, “it may be reasonable to add coQ10 in patients receiving long-term treatment with statins in general, and atorvastatin in particular. This recommendation is strengthened by the general experience that oral coQ10—even in high doses—is well tolerated by patients.” ( Rundek T et al, “ Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke,” Arch Neur , vol 16, June 2004, p 884-92.)

Printed with permission of Life Extension. For more information www.lef.org

 Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18. 

This page was last modified on Friday December 30, 2011