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Mega GLA 300 mg., 60 softgels |
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Omega-6 fatty acids are well supplied in the diet by meat and vegetable oils. However, not all omega-6 fatty acids are of equal value. Linoleic acid (not to be confused with ALA, which is in the omega-3 family) and arachidonic acid (AA) tend to be unhealthy because they promote inflammation. In contrast, Gamma-linolenic acid (GLA), found in evening primrose oil, borage oil, and black currant oil is an important fatty acid that plays a beneficial role in healthy prostaglandin formation. GLA (gamma-linolenic acid) is rapidly converted to dihomogamma-linolenic acid, the immediate precursor of prostaglandin PGE1 which is a potent anti-inflammatory agent. Gamma-linolenic acid (GLA) is an essential fatty acid (EFA) in the omega-6 family that is found primarily in plant-based oils. In the body, GLA is broken down to arachidonic acid (AA) and/or another substance called dihomogamma-liolenic acid (DGLA). Much of the GLA taken from the oils or as a supplement is not converted to AA, but rather to DGLA. DGLA competes with AA and prevents the negative inflammatory effects that AA would otherwise cause in the body. GLA, via conversion to prostaglandin E1 (PGE1), exhibits fluid-balancing and lipid-modifying potential. In addition, EFAs including GLA are important constituents of membrane phospholipids, including the mitochondrial membrane, where they enhance the integrity and the fluidity of the membrane. Other benefits of GLA include:
Caution: GLA, EPA and DHA have been shown to inhibit abnormal clotting within blood vessels (thrombosis). Most ischemic heart attacks and strokes are caused by abnormal arterial blood clots, so consuming these essential fatty acids may help protect against these types of cardiovascular diseases. Those taking anticoagulant drugs like Coumadin (warfarin) should inform their doctor that they are taking GLA, EPA, or DHA supplements, as the physician may want to adjust the dose of anticoagulant medication based on blood tests that measure coagulation factors such as prothrombin (PT). Since GLA, EPA, and DHA interfere with blood clotting, those who suffer from any type of hemorrhagic disease related to excessive bleeding or blood vessel leakage should consult their physician before supplementing these fatty acids. Scientists at the University of Pennsylvania reported that high doses of gamma-linolenic acid (GLA) were effective in treating rheumatoid arthritis patients. An earlier study by the same group had shown that administration of 1100 mg of GLA per day from borage seed oil reduced synovitis in six of seven patients with rheumatoid arthritis.
For rheumatoid arthritis patients, 5 capsules of GLA daily can be taken. Osteoarthritis patients may also benefit from using GLA. This product is effectively utilized when taken with meals, but not with fiber supplements. Product should be refrigerated. Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18. | ||||||||||||||||||||||||||||
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This page was last modified on Friday December 30, 2011 |