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Curcumin is a polyphenol (a plant sterol) present in the spice turmeric and was first used by Indians over 3,000 years ago in traditional Ayurvedic medicine. Modern science has found that curcumin has remarkable antioxidative, immunomodulatory, proapoptotic (helps modulate cell death), hepatoprotective and antiangiogenic properties.^1-6 Curcumin is also found to increase detoxifying enzymes and promote healthy DNA function.^7-11

Studies have tied inflammation to overexpression of a protein molecule called nuclear factor-kappa B (NF-kappaB). NF-kappaB acts like a switch to turn on genes that produce the body’s inflammatory responses. Because NF-kappaB’s expression increases in aging adults, scientists have sought ways to modulate NF-kappaB and its effects in the body.

Curcumin has been shown to exert powerful inhibitory effects on NF-kappaB activation within the body.¹² Curcumin inhibits overexpression of NF-kappaB. In addition, curcumin inhibits the metabolism of arachidonic acid, as well as activities of cyclooxygenase, lipoxygenase, and cytokines (interleukins and tumor necrosis factor).^13,14

Other clinical trials suggest roles for curcumin in helping maintain healthy lipid profile, bowel, and joint functions.^15,16 Curcumin can also help maintain normal healthy platelet function,^17-20 and have immunomodulatory effects by inhibiting histamine release from mast cells.²¹Other studies show curcumin’s potential for supporting healthy brain function and offering neuroprotection.^22-28

Curcumin may effectively support pancreatic islet health.^29,30 Curcumin’s multifaceted effects include protecting against estrogen-mimicking chemicals,^31,32 protecting against damaging free radicals, and promoting normal cell cycle growth.

Why is Life Extension's Super Bio-Curcumin better than other Curcumin products?

The problem is that curcumin is poorly absorbed into the bloodstream. Super Bio-Curcumin® absorbs up to seven times better than conventional curcumin. So this patented formula represents the most cost-effective way to supplement with this critical nutrient. Studies show that one 400 mg capsule a day of this turmeric compound can provide curcumin blood levels equal to ingesting 2,500–2,800 mg of commercial curcumin supplements. And not only does this turmeric formulation provide far greater peak blood levels, but the curcumin remains in the bloodstream almost twice as long as conventional supplements. And this enhanced absorption delivery complex provides other beneficial turmeric compounds in addition to standardized curcumin.

Each 400 mg capsule of Super Bio-Curcumin® is equivalent to 2,772 mg of a typical 95% curcumin extract.

Supplement Facts

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Bio-Curcumin® and BCM-95® are registered trademarks of Dolcas-Biotech, LLC. U.S. Patent Nos. 7,883,728, 7,736,679 and 7,879,373.

Dosage and Use
Take one capsule daily or as recommended by a health care provider.

Caution: Do not take if you have gallbladder problems or gallstones. If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product.

Printed with permission of Life Extension www.lef.org

References

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