Pregnenolone 50 mg. 100 capsules

Pregnenolone is biochemically, the “mother hormone,” made directly from cholesterol within the mitochondria, with the help of the p450scc enzyme. Pregnenolone being a precursor to various hormones can help the body to maintain normal hormone levels, which in turn help numerous body functions.^1-4

The following is a partial list of the diverse benefits of pregnenolone:

Memory enhancement
No negative feedback loop. Once produced, pregnenolone leaves the mitochondria so it cannot inhibit its own synthesis. By two different pathways, it converts to DHEA and progesterone (which cannot be made from DHEA).
Enzyme repair. Pregnenolone stimulates the cytochrome P-450 enzyme system which is important in neutralizing cellular toxins.
Protection from cortisol/cortisone. Cortisol levels increase with normal aging causing immune impairment, atherosclerosis, and neuronal injury. Pregnenolone protects against adrenal atrophy when withdrawing cortisone therapy, and helps protect against the effects of elevated cortisol including atrophy of the skin, osteoporosis, hot flashes in women and possibly adult-onset diabetes.

Supplement Facts

Serving size 1 capsule
Servings per container 100
Amount per serving
Pregnenolone	50 mg
Other ingredients: rice flour, gelatin, and water.

This product contains NO wheat, yeast, gluten, corn, or dairy. Contains NO sugar, artificial sweeteners, flavors, colors, or preservatives.

Dosage and use

Take one capsule one to four times daily, preferably early in the day on an empty stomach, or as recommended by a healthcare practitioner.

Caution:

Based on animal research, those who have a predisposition of brain seizures or suffer from epilepsy, may want to avoid pregnenolone. This precaution is based on proconvulsant activity pregnenolone induced when administered directly into the brain. When pregnenolone is orally ingested, it is metabolized in the liver in a way that causes it to work differently than when it is surgically introduced into an animal’s brain at artificially high doses. Pregnenolone may affect hormone levels. Those with hormonal cancers such as prostate or breast cancer should avoid pregnenolone.

Warnings:

Keep out of reach of children.
Do not exceed recommended dose.
When using nutritional supplements, inform your physician if you are undergoing treatment for a medical condition or are pregnant or lactating.

References
1. Biochem Pharmacol. 1995 Jan 6;49(1):1-16.
2. Proc Natl Acad Sci USA. 1992 Mar 1;89(5):1567-71.
3. Horm Metab Res. 1998 Jan;30(1):16-28. Review.
4. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12308-12.

Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18.

This page was last modified on Monday December 03, 2007