DHEA 50 mg., 100 capsules
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DHEA 50 mg., 100 capsules |
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UN207 $13.20
DHEA has been shown to improve memory and mood, increase lean body mass and improve neurological function and immune function. Consult a physician prior to taking DHEA. Ultimate Nutrition incorporates the highest quality standards in sourcing raw materials, manufacturing and packaging to ensure you, the consumer, the finest supplements available. DHEA It has been shown that the serum hormone DHEA often declines by 75–80% from peak levels by age 70 or later, leading to hormonal imbalances that can affect one’s quality of life.1-3 Peak blood levels of DHEA occur at approximately age 25, decreasing progressively thereafter.3 The marked decline in serum DHEA with age is believed to play a role in health problems associated with aging. Thus, scientists have been looking at ways of restoring DHEA to youthful levels to prevent or reverse those health issues, and are now discovering mechanisms by which DHEA protects against age-related decline. DHEA is the most abundant hormone in humans and other mammals, and it plays a critical role in many different bodily functions. In fact, decrease in DHEA levels is being increasingly used as an indicator of reduced immune response, loss of libido and lack of a sense of general well-being. The body produces DHEA in the adrenal gland using cholesterol as the starting material. It is metabolized to androstenedione, which is converted directly to testosterone. Like testosterone (estrogen in women) and other critical hormones, DHEA levels peak in the second or third decade of life, after which the decline begins. In men, roughly one-half of DHEA is lost by age 40. Reduced levels of DHEA mean reduced amounts of androstenedione, testosterone and other steroid hormone metabolites. It is interesting to note that as cholesterol in general increases with age, DHEA levels decrease. As a result, DHEA deficiency is associated with an array of chronic conditions, such as obesity, diabetes, high blood pressure, coronary artery disease, and various immune deficiencies, including autoimmune diseases. DHEA directly affects glucose metabolism. High blood glucose inhibits growth hormone (GH) and low blood glucose stimulates growth hormone. Stimulation of growth hormone is beneficial to DHEA, because it suppresses insulin. By the same token, fasting increases both GH and DHEA. Thus, the importance of DHEA in intense exercise and endurance training can hardly be overemphasized. In fact, Dr. William Regelson of Medical College of Virginia in his book The Superhormone Promise calls DHEA "the superstar of hormones" and "one of the most powerful tools" available for enhancing and extending life. Clinical results show that oral supplementation with DHEA can have numerous beneficial effects including:.
DHEA usage and safety precautionsLife Extension® has been investigating DHEA for almost 30 years. Life Extension’s DHEA directions for use are specially drafted to provide optimal, but safe dosing. The standard blood test to evaluate DHEA status is one that measures DHEA sulfate levels (DHEA-S). The DHEA-S is calculated in micrograms per deciliter (μ/dL) of blood. A DHEA-S (dehydroepiandrosterone sulfate) blood test may be taken three to six weeks after initiating a DHEA supplementation regimen to help determine optimal dosing. When having your blood tested for DHEA, blood should be drawn three to four hours after the last dose. DHEA testing may save you money if it shows you can take less DHEA to maintain youthful DHEA serum levels. Because of the overwhelming evidence connecting low levels of DHEA to problems associated with aging, Life Extension suggests that all people over age 40 begin DHEA therapy. For most people, the starting dose of DHEA is between 15–75 mg, taken in one daily dose. Many studies have used a daily dose of 50 mg. Ideally, DHEA replacement therapy should begin with blood testing to establish a base range. Since almost everyone over age 35–40 has lower than optimal levels of DHEA, most people begin supplementation and test their blood DHEA levels later to make sure they are taking the proper dose. Normal serum reference ranges and ideal ranges of DHEA-S are:
People over age 40 who do not supplement with DHEA usually have serum levels below 200, and many are below 100 as a steady decline takes place after the third decade in life.1,12,14 There are different precautions for men and women that should be observed. DHEA precautions for menBefore attempting to restore DHEA to youthful levels, men should know their serum PSA (prostate specific antigen) level. Men with prostate cancer or severe benign prostate disease are advised to avoid DHEA since it can be converted into testosterone (and estrogen). Therefore, men are advised to have a PSA and digital rectal exam before initiating DHEA to rule out existing prostate disease. It is important for men over 40 to have a physician check their PSA and DHEA-S serum levels every six to twelve months thereafter. Men should also periodically check their blood levels for free testosterone and estrogen to make sure that DHEA is following a youthful metabolic pathway. DHEA precautions for womenWomen should consider estrogen and testosterone testing when they take their DHEA blood test in order to evaluate DHEA’s effect on their blood levels of these hormones. Women who have been diagnosed with an estrogen-dependent cancer should consult their physicians before beginning the DHEA restoration process. Warning: Not recommended for pregnant, nursing women or any person who is under 35 years of age. Seek the advise of your licensed health care practitioner before using this product .
Suggested Use: One (1) capsule daily with a meal or as recommended by a health care professional.
SELECTED REFERENCES 1. J Clin
Endocrinol Metab. 1992 Oct;75(4):1002-4. FREQUENTLY ASKED QUESTIONS 1) What is the Difference between DHEA and DHEA Sulfate? The total DHEA in the blood is a combination of free DHEA and DHEA sulfate (DHEA-S), which is a DHEA molecule with a sulfur atom attached to it. Although no distinction is normally made between DHEA and DHEA-S, it should be noted that DHEA-S functions as a ready reservoir of weakly bound DHEA. 2) Does Oral DHEA Supplementation Work? Numerous studies, some of which are listed in the references above, have shown that oral DHEA works quite efficiently. Intake of as small an amount as 100 mg DHEA each day can result in remarkable increase in both physical and psychological wellbeing. It helps improve muscle mass and muscle strength is increased. Since it is a powerful hormone, in cases of any clinical conditions, it should be taken under clinical supervision and in consultation with your primary care physician. 3) When Should One Use DHEA Supplementation? If the DHEA levels in the bloodstream drop below a certain value --normally, 180 ng/dL in women and 220 ng/dL in men-- DHEA supplementation may become necessary. Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18.
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This page was last modified on Friday December 30, 2011 |
