Bone Restore 150 tablets

There are dietary supplements designed to prevent and treat osteoporosis. A product called Bone Restore provides the better-documented nutrients for the prevention and treatment of osteoporosis.

A problem overlooked by most doctors is that loss of bone density is associated with deficiencies of not just calcium, but a host of other nutrients including magnesium and vitamin D3.^1-6 In order for calcium to prevent bone loss, adequate amounts of vitamin D3, zinc, manganese and other nutrients should be available so that calcium, magnesium, and phosphorus can be incorporated into the bone matrix.^7-15 Another issue that many people are not aware of is that many forms of calcium do not absorb particularly well.^16-17

In order to overcome the impediments that preclude aging women from achieving optimal calcium status, a mineral formula has been designed that provides 1200 elemental milligrams from three different forms of calcium per daily dose, along with critically important nutrients needed to promote healthy bones. Bone Restore™ provides calcium along with nutrients such as boron and silicon to further boost the body’s ability to maintain healthy bone density.^18,19*

Boron has been identified as one of the most important nutrients to help maintain bone health. As such, Life Extension has incorporated a powerful form of boron, called FruiteX B® OsteoBoron™, which is more bioavailable than boron citrate, the nutrient used in most commercial bone building supplements.

FruiteX B® OsteoBoron™, is a natural boron/fructose/carbohydrate complex, similar to what is found in fruits and vegetables. Its unique boron-carbohydrate structure that easily binds to fructose may be one of the reasons for its health benefits.

Boron in general is a crucial mineral in bone/joint health. Numerous studies have shown boron to contribute to the structural integrity of bone.^20-22

Many people in North America who consume an average diet have magnesium deficiency, and magnesium is important in bone structure. Magnesium deficiency comes about because most magnesium in our diet comes from the magnesium contained in the chlorophyll molecule found mainly in dark green leafy vegetables--not something that most people eat on a daily basis. Magnesium intake should be about half that of calcium, approximately 300-500 mg per day. If not provided in the diet, then magnesium should be supplemented. Some researchers are now also reporting that magnesium deficiency plays a significant role in the development of osteoporosis (Dreosti 1995). Studies have shown that women with osteoporosis tend to have a lower magnesium intake than normal and lower levels of magnesium in their bones. Recommendations for postmenopausal women to increase calcium intake can lead to an unfavorable Ca to Mg ratio unless the magnesium intake is increased accordingly; the optimum ratio of Ca to Mg is believed to be 2:1. A magnesium deficiency can also affect the production of the biologically active form of vitamin D, thereby further promoting osteoporosis. Some research shows that magnesium supplementation is effective in treating osteoporosis. Magnesium supplementation (over and above the current recommended daily allowance) may suppress bone turnover in young adults and some researchers speculate that it may also help prevent age-related osteoporosis (Dimai et al. 1998).

Significant calcium imbalance can come about as a result of high intakes of phosphorus. Phosphorus is present in high quantities in protein-containing foods and soft drinks. There is some evidence that due to the large increase in soft drinks in the last decade that this factor alone may contribute to poor peak bone mass in younger individuals. Based on data from more than 4000 children aged 2-17 years, soda consumption among children and adolescents rose 41% in the time period of 1989-1991 compared to 1994-1995. This displaced milk and juice, which are the leading sources of many vitamins and minerals in the American diet (Wyshak 2000). A 1994 study of 127 children aged 8-16 found that 39% of the girls and 41% of the boys had a history of bone fracture. Girls who consumed greater amounts of cola beverages had a higher incidence of fractures than those who consumed low amounts. A high calcium intake was found to protect against fractures, particularly among girls who had high physical activity (Ballew et al. 2000).

Because other trace minerals have been implicated in osteoporosis, the following regimes are recommended by health care professionals for mineral supplementation:

Obtain as much calcium and magnesium and other trace minerals from your diet as possible by drinking milk (if tolerated) and eating dark green leafy vegetables, broccoli, nuts, and seeds; eliminate or reduce the use of colas and other soft drinks in order to decrease phosphorus intake.
Postmenopausal women should probably supplement with calcium/magnesium capsules. Daily intakes should reach at least 1000 mg of calcium and 300-500 mg of elemental magnesium, along with sufficient trace minerals including boron, and copper.
For bone mineral maintenance and replacement, the Life Extension Foundation recommends that women take at least 1000 mg of elemental calcium along with 300-500 mg of elemental magnesium every day.
The addition of between 400-1000 IU of vitamin D3 is mandatory to ensure optimal calcium absorption.

The inability to absorb calcium is a major reason that calcium therapy fails to prevent or slow the progression of osteoporosis. Vitamin D3 taken with calcium will normally promote absorption and assimilation of calcium into the bone matrix. Vitamin D3 has also been shown to promote the production of IGF-I and other growth factors in osteoporotic patients, which improves osteoblast (bone-building) function. Other minerals that are important for healthy bone metabolism include boron, zinc, manganese and silicon.
The recommended dose is 5 capsules per day.-- It is best to take calcium supplements with meals. Although certain fibers, such as wheat bran, psyllium, guar gum, and pectin, can interfere with mineral absorption, calcium absorbs better with meals. The recommended time to take Bone Restore would be at bedtime.

Supplement Facts

Serving Size 5 capsules
Servings Per Container 30
Amount Per Serving
Vitamin D3 (as cholecalciferol)	1000 IU
Calcium (as dicalcium malate, calcium bis-glycinate, calcium fructoborate)	1200 mg
Magnesium (as magnesium oxide)	340 mg
Zinc (as zinc amino acid chelate)	2 mg
Manganese (as manganese amino acid chelate)	1 mg
Boron (calcium fructoborate as patented Fruitex B® OsteoBoron™)	3 mg
Silicon (from horsetail herb, Equisetum arvense)	5 mg
Other ingredients: gelatin, magnesium stearate.

Dosage and Use
Take five capsules at dinner or before bedtime, or as recommended by a healthcare practitioner.

Fruitex B® is a registered trademark of VDF Futureceuticals, Inc.

OsteoBoron™ is a trademark of VDF Futureceuticals, Inc.

References

1. Magnes Trace Elem. 1990;9(2):61-9.
2. Curr Pharm Des. 2003;9(32):2687-704.
3. Biol Trace Elem Res 28:243-55, 1991.
4. Magnes Res. 1993 Jun;6(2):155-63.
5. J Reprod Med. 1990 May;35(5):503-7.
6. Gynecol Endocrinol. 1994 Mar;8(1):55-8.
7. J Nutr Sci Vitaminol ( Tokyo). 1999 Oct;45(5):509-17.
8. J Natl Cancer Inst. 2004 Jun 16;96(12):921-5.
9. Curr Pharm Des. 2003;9(32):2687-704.
10. J Nutr. 1994 Jul;124(7):1060-4.
11. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:288-95.
12. Bone. 2003 Feb;32(2):127-35.
13. Magnes Res. 1993 Sep;6(3):247-9.
14. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:60-3.
15. Am J Clin Nutr. 1995 Mar;61(3 Suppl):638S-45S.
16. Methods Find Exp Clin Pharmacol. 1995 Sep;17(7):437-42.
17. Nutr Rev. 1992 Feb;50(2):33-40. Review.
18. Magnes Trace Elem 1990;9:61-9.
19. FASEB J 1987;1:394-7.
20. Environ Health Perspect. 1994 Nov;102 Suppl 7:83-5.
21. Crit Rev Food Sci Nutr. 2003;43(2):219-31. Review.
22. Prog Food Nutr Sci. 1993 Oct-Dec;17(4):331-49. Review.

Warnings

Keep out of reach of children.
Do not exceed recommended dose.
If you have a bad reaction to this product, discontinue use.
When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18.

This page was last modified on Wednesday July 30, 2008