Life Extension One Per Day tablets

Life Extension is an organization with a track record of not backing down on positions that are believe to be scientifically supported. The Life Extension Foundation (LEF) contends that to achieve the best possible benefits from dietary supplements, sufficient potencies of active ingredients must be taken on a daily basis. When the first version of Life Extension Mix was formulated in 1983, some people balked at having to take nine tablets per day to obtain the recommended daily dose. Up until recently, LEF refused to waiver on the position that nine tablets are required to accommodate the nutrients needed for optimal disease protection.

While most Foundation members use Life Extension Mix, many people won't take nine tablets per day, even though their lives may depend on it. This has frustrated Life Extension members because they want to recommend a one-per-day supplement that will supply some degree of disease risk reduction to those they care for.

Obtaining partial protection in one tablet

There are studies showing that low potency supplements do not provide disease risk reduction benefits.1 On the flip side are nutrients like folic acid for which reductions in certain disease risks occur in any amount taken in supplemental form.2 The same holds true for micronutrients like zinc , for which mortality reductions occur in those consuming relatively small amounts from supplements.3,4

So if a person is only willing to take one supplement per day, there is at least a basis for asserting that there will be some benefit compared to taking nothing. In response to requests for a scientifically based one-per-day tablet, Life Extension Buyers' Club has compounded a formula that provides the greatest potencies of nutrients that can fit into one tablet. The primary objective in introducing this formula is to enable Life Extension members to recommend a supplement that their friends and family will take on a daily basis. Those members who take most of the ingredients in Life Extension Mix individually may also use this supplement to conveniently fill in the missing gaps.

The Life Extension One-Per-Day Tablet is designed for people who are not willing to take high-potency supplements such as the multi-ingredient Life Extension Mix formula. It provides adequate amounts of nutrients to statistically reduced one's risk of contracting certain degenerative diseases. Compared to popular "one-a-day" supplements like Centrum®, it contains far higher potencies.

References

1 Evangelou A, Kalpouzos G, Karkabounas S, Liasko R, Nonni A, Stefanou D, Kallistratos G. Dose-related and therapeutic effects of antioxidants-anticarcinogens on experimentally-induced malignant tumors in Wistar rats. Cancer Lett. 1997 May 1; 115(1):10511.

2. Giovannucci E, Stampfer MJ, Colditz GA, Hunter DJ, Fuchs C, Rosner BA, Speizer FE , Willett WC, Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study. Ann Intern Med. 1998 Oct 1;129(7):517-24.

3. Losonczy KG, Harris TB, Havlik RJ. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly. Am J Clin Nutr. 1996 Aug;64(2):190-6.

4. Khaw KT, Bingham S, Welch A, Luben R, Wareham N, Oakes S, Day N. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.

Lancet. 2001 Mar 3;357(9257):657-63.

Supplement Facts
Serving Size: 1 tablet
Servings Per Container: 60
Amount Per Serving

Vitamin A (as 20% beta-carotene, as 80% palmitate )	5000 IU
Vitamin C (as ascorbic acid, niacinamide and calcium ascorbates)	500 mg
Vitamin D (as cholecalciferol)	800 IU
Vitamin E (as D-alpha-tocopheryl succinate)	200 IU
Thiamine (vitamin B1) (as thiamine HCl)	75 mg
Riboflavin (vitamin B2)	50 mg
Niacin (vitamin B3) (as niacinamide ascorbate)	50 mg
Vitamin B6 (as pyridoxine HCl)	75 mg
Folic acid	800 mcg
Vitamin B12 (as cyanocobalamin)	300 mcg
Biotin	300 mcg
Pantothenic acid (as D-calcium pantothenate)	100 mg
Calcium (from dicalcium phosphate, D-calcium pantothenate, and calcium ascorbate)	20 mg
Iodine (from Atlantic kelp)	150 mcg
Magnesium (as magnesium oxide)	100 mg
Zinc (as OptiZinc® zinc DL-methionine complex)	30 mg
Selenium (as L-selenomethionine)	100 mcg
Manganese (as manganese gluconate)	2 mg
Chromium (as chromium polynicotinate)	200 mcg
Molybdenum (as molybdenum amino acid chelate)	100 mcg
Potassium (as potassium citrate)	25 mg
Alpha-carotene	50 mcg
Boron (as boron amino acid chelate)	3 mg
Choline (bitartrate)	23.9 mg
Inositol	50 mg
Biolut™ Marigold Extract (Tagetes erecta) (flowers) [std. to 45% free Lutein equivalent ( 5 mg), 2% zeaxanthin (220 mcg)]	11 mg
Lycopene (as Lyco-O-Mato™ tomato extract)	2 mg
PABA (para-aminobenzoic acid)	30 mg

Other ingredients: dicalcium phosphate, microcrystalline cellulose, maltodextrin, stearic acid, magnesium stearate, croscarmellose sodium, silicon dioxide, purified water, methylcellulose, polyethylene glycol.

Contains soybeans. Contains corn and rice. This product contains NO milk, egg, fish, peanuts, crustacean shellfish, tree nuts, wheat, yeast, gluten, or artificial sweeteners.

Lyc-O-Mato® is a registered trademark of LycoRed Natural Products Industries, Ltd.
OptiZinc® is a registered trademark of InterHealth Nutritionals, Inc.
Biolut™ is a trademark of Biolut SA de CV.

Dosage and Use
Take 1 tablet a day with meals, or as recommended by a healthcare practitioner.

Caution Keep out of reach of children.

If you become ill after taking the product, please consult your physician.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to the product, discontinue use immediately.
When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition.

Store tightly closed in a cool, dry place.

This page was last modified on Thursday July 03, 2008