Health and Sport logo

Life Extension Mix w/o copper, 315 tablets

 Home Page   Whats New ?   How To Order   Shipping Policy   Customer Service  Contact Us

 

      
Click Here for Recommended Books

 

Search for:

 

Email Newsletter icon, E-mail Newsletter icon, Email List icon, E-mail List icon Sign up for our Email Newsletter

Go Directly To Store

View/Buy From  Product List

View Basket Contents

Monthly Specials

Personal Training

Newsletter Archive

Amino Acids

Anti-Aging/Cardiovascular

Anti-inflammatory/Joint Health

Cancer Adjuvant Therapies

Cookies

Digestive Health

Energy

Fiber/Cholesterol Lowering

Fish Oils/EFAs

Gift Baskets

Herbs/Phyto-Extracts

Hormone Support

Immune Function

Ketogenic

Men's Health

Minerals

Miscellaneous

Personal Care

Protein Powders

Sports Supplements

Stevia

Vitamins

Weight Management

Weight Training Accessories

Women's Health

View Catalog

Healthy Links

 


         Best Web Hosting

 

 

 

        

 

                           Life Extension Mix Without Copper 315 tabs.

                                           LE1245
         Life Extension Mix without Copper, 315 tablets

                                          $69.75

                                        Buy Me
                                      

Why Choose Life Extension Mix WITHOUT Copper?

Some evidence points to patients with Wilson’s disease (an inherited genetic defect that causes a buildup of copper and the inability to release the metal), have signs of lipid peroxidation in their livers. Wilson’s disease can result in damage to the liver, kidneys, brain and eyes, as well as anemia (due to compromised iron absorption), jaundice and softening of the bones.

Published scientific studies document that people who eat the most fruits and vegetables have much lower incidences of health problems. Few people, however, consistently eat enough plant foods to protect against common age-related decline,1-3 and commercial multivitamins do not provide all of the vital plant components needed to maintain good health. Life Extension Mix provides concentrations of the fruit and vegetable extracts that researchers have found to be protective against a wide variety of cellular insults.

Life Extension Mix™ contains 92 unique vegetable, fruit, and herbal extracts along with high-potency amino acids, vitamins, minerals, and special antioxidants. The formula is fortified with botanical extracts that help maintain healthy cells via physiological processes separate from traditional antioxidants. Cooking can destroy key nutrients and enzymes in vegetables depleting them of their health benefits. Commercial agriculture processes often result in fruits and vegetables that have not reached maturity and optimal nutrient content. Life Extension Mix provides key compounds found in vegetables and antioxidants found in fruits that are often lost in food production and processing.

Epidemiological studies show that increased intake of polyphenols is associated with a reduced risk of major cardiac events. The ability of cocoa polyphenols to support endothelial function by maintaining healthy nitric oxide levels is the primary protective mechanism. The secondary benefit of suppressing dangerous inflammatory factors is another manner by which cocoa polyphenols may reduce cardiovascular risks.4-8 The Life Extension Mix formula has been upgraded to provide 30 mg of standardized cocoa polyphenols in each daily dose. Based on the research this is the minimum potency of cocoa polyphenols that healthy people will benefit from consuming each day.

Life Extension Mix also contains:

High potency green tea. Life Extension Mix provides 325 mg of a decaffeinated green tea extract that is standardized to contain 98% (318.5 mg) of polyphenols and 45% (146.25 mg) of epigallocatechin gallate EGCG) to which scientists attribute green tea's health benefits.9-15 The amount of polyphenols (including EGCG) in Life Extension Mix is equivalent to drinking 3-6 cups of green tea per day. Scientists have identified multiple mechanisms by which green tea extract protects against LDL oxidation, neuronal oxidation, and a host of other structural and functional age related changes.

Fruit and vegetable extracts

Luteolin is a flavonoid found in parsley, artichoke, basil, celery and other foods. When measured against 27 other flavonoids, luteolin provided the best DNA protection. One favorable mechanism of luteolin is its ability to inhibit oxidative damage to cellular DNA. Another unique benefit is luteolin's ability to suppress excess levels of dangerous inflammatory cytokines such as interleukin-6 and interleukin 1B.16 Life Extension Mix contains a standardized dose of 8 mg luteolin.

Broccoli is touted as one of the most important vegetables to help maintain healthy DNA. Broccoli contains several active constituents, with sulphoraphane being the most significant because of its unique detoxification and DNA protecting effects. Life Extension Mix provides a concentrated broccoli mixture that provides standardized extracts of sulphoraphane and glucosinolates, two compounds attributed to broccoli's multiple protective benefits. Broccoli is also a natural source of gene protecting chlorophyll.*17-21

D-glucarate is a botanical extract found in grapefruit, apples, oranges, broccoli and Brussels sprouts. D-glucarate effectively supports a detoxification process that helps to remove DNA toxins from the body.22,23 The daily dose of Life Extension Mix provides 200 mg D-glucarate.

Lutein, an extract found in spinach and collard greens, has been shown to help maintain critical pigments in the eye macula, while the carotenoid alpha-carotene has demonstrated antioxidant activity far grater than beta-carotene. Lycopene is the red carotenoid in tomatoes has shown potent effects in helping to maintain healthy DNA structure. Lycopene also protects against LDL oxidation, and aids in maintaining a healthy prostate. Life Extension Mix contains 60 times more lutein and 10 times more lycopene compared to Centrum®. Most multivitamin supplements provide no vegetable extracts.

Life Extension Mix is fortified with fruit extracts such as bilberry, grape seed, grape skin, and citrus bioflavonoids to provide healthy circulation throughout the body and maintain healthy DNA.*

The media has publicized the multiple benefits of fruits such as blackberry, cranberry, elderberry, cherry, plums and persimmon. Life Extension Mix has a customized blend of these and other fruits that studies indicate provide multiple favorable effects in the body.

Pomegranate extract standardized to provide the punicalagins and other polyphenols found in up to 2.6 ounces of pomegranate juice.

Wild blueberry extract, concentrated and standardized, has been added to provide optimal beneficial effects.

Olive oil consumption is one of the important factors behind the health benefits of the "Mediterranean Diet."24,25 Researchers have discovered that there are up to 300 times more polyphenol compounds in olive water compared to olive oil.26,27 Olive polyphenols have been the subject of numerous studies pointing toward their benefits in many different areas, including helping to protect against LDL oxidation, suppressing free radicals, and stabilizing cell membranes.28-30 Life Extension Mix contains a potent olive juice extract standardized to contain 7 percent of the best-documented polyphenol called hydroxytyrosol.31 The amount of hydroxytyrosol in Life Extension Mix is equivalent to drinking one ounce of virgin olive oil per day.32-33

Sesame lignans enhance the effects of vitamin E. Sesame and its lignans have a broad range of applications in human health. This includes increasing human tissue levels of vitamin E by facilitating carrier proteins in the liver to deliver nutrients to cells throughout the body.34,35

Sesame lignans increase the anti-inflammatory index of fish oils and help maintain healthy cholesterol/LDL levels in those already within normal range.*36-39 Life Extension Mix contains 10 mg sesame lignan extract to provide the direct benefits of the lignans and augment the effects of vitamin E and other nutrients in the body such as gamma-tocopherol and gamma-linolenic acid (GLA).

Vitamins

Pyridoxal 5-phosphate helps protect against glycation reactions, a toxic process by which sugars bind to proteins to form nonfunctional structures in the body.

High potency vitamin D3: Doctors used to be concerned that too much vitamin D could be toxic. Over the past few years, however, an increasing body of evidence indicates that it takes much higher doses of vitamin D (perhaps over 10,000 IU/day) to result in toxicity in a healthy person. The concern expressed by researchers today is that fear of vitamin D toxicity is keeping many people from supplementing with enough vitamin D, which is critical for maintaining bone density. In response to studies showing that even those who take standard vitamin D supplements are not obtaining adequate amounts, Life Extension Mix provides 800 IU vitamin D3 per daily dose.

Life Extension Mix™ contains only the dry powder form of vitamin E. This natural form of vitamin E (succinate) has been shown to promote healthy DNA better than other forms.

Amino Acids

N-acetyl-cysteine suppresses free radicals inside the cells and maintains healthy glutathione levels. Taurine may protect against free radicals between cells and supports eye health.

Minerals

Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer; however, the FDA has determined that this evidence is not conclusive.

Zinc is often poorly absorbed, but Life Extension Mix™ provides two of the most bioavailable forms of zinc.

Boron is not only needed to maintain healthy bone density, but may also help promote healthy prostate cell development.

Chromium: Life Extension Mix contains a superior and biologically active trivalent chromium complex, a unique food form bio-organic water soluble matrix. Chromium, along with magnesium and biotin, are nutrients required to maintain healthy blood sugar levels in those already within normal range.40,41

Higher potency magnesium: Magnesium is needed for more than 300 biochemical reactions in the body. It helps maintain normal muscle and nerve function, keeps heart rhythm steady, supports a healthy immune system, and keeps bones strong. Magnesium also helps maintain healthy blood sugar and blood pressure levels in those already within normal range, and is known to be involved in energy metabolism and protein synthesis.

Cholinergic nutrients

Maintaining high levels of acetylcholine in the brain by consuming choline helps correct mild memory problems associated with aging and helps protect against age-associated mental decline.

Life Extension Mix saves time and money by combining the most popular nutrient supplements in one product, eliminating the need to take separate bottles of B-complex, vitamins C and E, mineral supplements and much more that would be required to achieve the same effects. Life Extension Mix supplies the most powerful antioxidants, including water and fat soluble vitamin C, the ideal form of alpha vitamin E, and plant extracts that help protect against cellular DNA damage. Other ingredients in Life Extension Mix enhance beneficial DNA methylation patterns, and help maintain glycemic control and healthy levels of LDL in those already within normal range. Life Extension uses standardized herbal extracts to ensure that our products contain the highest level of biological activity.

Supplement Facts
Serving Size 9 tablets (per day)
Servings Per Container 35
Vitamin A (as 20% Betatene® D. salina natural beta-carotene with mixed carotenoids1, and 80% acetate) 5,000 IU
Vitamin C (as ascorbic acid8, calcium ascorbate, ascorbyl palmitate, magnesium ascorbate, niacinamide ascorbate, and acerola juice powder) 2000 mg
Vitamin D3 (as cholecalciferol) 800 IU
Vitamin E (as D-alpha tocopheryl succinate) 400 IU
Thiamine (vitamin B1) (as thiamine HCl8) 125 mg
Riboflavin8 (vitamin B2) (with 2 mg riboflavin 5’ phosphate coenzyme) 50 mg
Niacin8 (vitamin B3) (as 53% niacinamide, 38% niacin, 9% niacinamide ascorbate) 190 mg
Vitamin B68 (as pyridoxine HCI with 2.5 mg pyridoxal 5’ phosphate coenzyme) 100 mg
Folic acid 800 mcg
Vitamin B12 (as 42% cyanocobalamin, 42% hydroxylcobalamin, 16% ion exchange 600 mcg
Biotin 3000 mcg
Pantothenic acid (as D-calcium pantothenate8 with 5 mg pantethine) 600 mg
Calcium (as calcium ascorbate, calcium pantothenate, Calcium D-Glucarate2) 218 mg
Iodine (as potassium iodide) 75 mcg
Magnesium (as magnesium oxide, citrate, glycinate, taurinate, arginate, ascorbate ) 400 mg
Zinc [as methionate (Optizinc®3), zinc succinate] 35 mg
Selenium (as 50% se-methylselenocysteine, 25% L-selenomethionine (yeast free) (SelenoPure™4), and 25% sodium selenate) 200 mcg
Manganese (as manganese gluconate)

1 mg

Chromium (as Chromium 454™5 bio-organic yeast extract matrix) 500 mcg
Molybdenum (as sodium molybdate) 125 mcg
Potassium (as potassium chloride) 37.4 mg
N-Acetyl-L-cysteine (NAC) 600 mg
Taurine 200 mg
Choline (as choline bitartrate) 120 mg
Inositol 250 mg
Phosphatidylcholine (from soy) 150 mg
Bromelain (from pineapple) (2400 gelatin digestive units per gram) 15 mg
para-aminobenzoic acid (PABA) 200 mg
Trimethylglycine (TMG) (as betaine anhydrous) (from sugar beets) 100 mg
Alpha-carotene 100 IU
VitaBlue®9 Wild Blueberry (Vaccinium angustifolium)
  130:1 Extract (fruit) [standardized to 14% Total Phenolics (21 mg),    4.9% Total Anthocyanins (7.35 mg), 660 ppm Pterostilbene (0.1 mg)]
150 mg
Bilberry extract (Vaccinium myrtillus) (berry) [standardized for 25% anthocyanidins (7.5 mg)] 30 mg
Citrus bioflavonoid complex [50% total bioflavonoids (100 mg)]
Typical profile: (to equal 50% total bioflavonoids)
Flavanone (Hesperidin) 35% (70 mg)
Flavonones (Naringin, Naringenin 7-B-Rutinoside and others) 14% (28 mg)
Flavonols, Flavones and related phenolic compounds 1% (2 mg)
200 mg
Broccoli sprout concentrate
(A proprietary blend of broccoli sprout concentrates and Calcium D-Glucarate2) (providing sulforaphane, glucosinolates, D-3T, and PEITC)
525 mg
Calcium D-Glucarate2 200 mg
Decaffeinated Green tea (Camellia sinensis) extract (leaf)
[std. to 98% polyphenols (318.5 mg) and 45% Epigallocatechin gallate (EGCG) (146.25 mg)]
325 mg
Acerola juice powder extract 1:4 (Malpighia punicifolia L.) (fruit) 300 mg
Ginger root extract (Zingiber officinale) (root) [standardized for 5% gingerols (10 mg)] 200 mg
HiActives 100% fruit/berry complex (A proprietary blend of concentrated blackberry, blueberry, cranberry, elderberry, persimmon, plum, and cherry powders) 200 mg
CocoaGold™ Cocoa (Theobroma cacao L.) extract (bean) [std. to 45% polyphenols (30 mg)] 67 mg
Milk thistle extract (Silybum marianus) (seeds) [standardized for 85% silymarin (85 mg)] 100 mg
Pomegranate (Punica granatum) extract (fruit) [standardized to 30% Punicalagins (25.5 mg)] 85 mg
Bilberry extract (Vaccinium myrtillus) (berry) [standardized for 25% anthocyanidins (7.5 mg)] 30 mg
Leucoselect®6 grapeseed extract (Vitis vinifera) (seeds) [standardized for 95% proanthocyanidins (23.75 mg)] 25 mg
BioVin®7 full spectrum grape extract (Vitis vinifera L.) (whole grapes) [standardized to 95% proanthocyanidins (23.75 mg), 75% total polyphenols as gallic acid monohydrate (18.75 mg), 200 ppm trans-resveratrol] 25 mg
Bromelain (from pineapple) (2400 gelatin digestive units per gram) 15 mg
Lutein (purified concentrate from marigold flowers) (Tagetes erecta) (providing 465 mcg zeaxanthin) 15 mg
Sesame (Sesamum indicum) lignan extract 10 mg
Lycopene (from natural tomato extract) (LYC-O-MATO®9) 3 mg
Luteolin [from Perilla leaf extract (Perilla frutescens)] 8 mg
Olive juice extract (fresh fruit) [std. to 50% polyphenols (6.25 mg), 6% hydroxytyrosol (0.75 mg)] 12.5 mg
Other Ingredients: rice flour, gelatin, magnesium stearate. Contains milk, soybeans, tree nuts (cocoa beans). Contains corn, rice, and sesame. This product contains NO egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), wheat, yeast or gluten. Contains NO artificial sweeteners, flavors, or colors.

References

1. Fung TT et al. Stroke. 2004 Sep;35(9)2014-9.
2. Ferguson LR. Mutant Res. 1999 Jul 16;428(1-2):329-38.
3. Steinmetz KA, Potter JD.J Am Diet Assoc. 1996 Oct;96(10):1027-39.
4. Am J Clin Nutr. 2005a Jan;81 (1 Suppl):304S-312S.
5. J Nutr. 2004;134:923–926.
6. Free Radic Biol Med. 2004;37:1351–1359.
7. Clin Dev Immunol. 2005;12:11–17.
8. Am J Clin Nutr. 2007 Mar;85(3):709-17.
9. Fassina G, Vene R, Morini M et al, Mechanisms of inhibition of tumor angiogenesis and vascular tumor growth by epigallocatechin-3-gallate. Clin Cancer Res. 2004; 10(14):4865-73.
10. Yang CS, Chung JY, Li C et al. Mechanisms of inhibition of carcinogenesis by tea. Biofactors 2000;13:91-4):73-9.
11. Fujiki, H. Two stages of cancer prevention with green tea. J Cancer Res Clin Oncol 1999 Nove;125(11):589-97.
12. Xu JZ, Yeung SY, Chang Q et al. Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br J Nutr. 2004 Jun;91(6):873-81.
13. Miyazawa T. Absorption, metabolism and antioxidative effects of tea catechins in humans. Biofactors 200;13(1-4):55-9.
14. Xie D, Liu G, Ghu G et al. [-]-Epigallocatechin-3-gallate protects cultured spiral ganglion cells from H2O2-induced oxidizing damage. Acta Otolaryngol. 2004 May;124(4):464-70.
15. Beliveau R, Gingras D. Green tea prevention and treatment of cancer by nutriceuticals. Lancet 2004 Sep 18;364(9439):1021-2.
16. Kotanidou A. Luteolin reduces lipolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice. Am J Respir Crit Care Med, 2003 Mar 15;165(6):818-23.
17. Zhang Y, Callaway ED. High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter-mediated export as a glutathione conjugate. Biochem J. 2002 May 15:364(Pt 1):301-7.
18. Faulkner K, Mithen R. et al. Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl gluosinolate in broccoli. Carcinogenesis. 1998 Apr;19(4):605-9.
19. Vang O, Frandsen H, et al. Biochemical effects of dietary intakes of different broccoli samples. I. Differential modulation of cytochrome P-450 activities in rat liver, kidney, and colon. Metabolism. 2001 Oct;50(10):1123-9.
20. Vang O, Mortensen J, et al. Biochemical effects of dietary intake of different broccoli samples. II. Multivariate analysis of contributions of specific glucosinolates in modulating cytochrome P-450 and antioxidant defense enzyme activities. Metabolism. 2001 Oct;50(10):1130-5.
21. Smith TK, Mithen R, Johnson IT. Effects of brassica vegetable juice on the induction of apoptosis of aberrant crypt foci in rat colonic mucosal crypts in vivo. Carcinogenesis 2003 Mar;24(3):491-5.
22. Hanausek M, Walaszek A, Slaga TJ. Detoxifying cancer causing agents to prevent cancer. Integr Cancer Ther. 2003 Jun;2(2):139-44.
23. Walaszek Z, Szemjaf J, Narag M et al. Metabolism, uptake and excretion of a D-glucaric acid salt and potential use in cancer prevention. Cancer Detect Prev. 997;21(2):178-90.
24. Visioli F, Galli C. Biological properties of olive oil phytochemicals. Cri Rev Food Sci Nutri. 2002; 42(3):209-21.
25. Valavanidis A, Nisiotou C, Papageoriou Y et al. Comparison of the radical scavenging potential of polar and lipidic fractions of olive oil and other vegetable oils under normal conditions and after thermal treatment. J Agric Food Chem. 2004 Apr 21;52(8):2358-65.
26. Ranalli A, Lucer L, Contento S. Antioxidizing potency of phenol compounds in olive mill wastewater. J Agric Food Chem. 2003 Dec 17;51(26):7636-41.
27. Water-soluble olive polyphenols. Technical file, Inosud S.A. Groupe La Gardonnenque, updated 31/01/2003.
28. Valavanidis A, Nisiotou C, Papageoriou Y et al. Comparison of the radical scavenging potential of polar and lipid fractions of olive oil and other vegetable oils under normal conditions and after thermal treatment. J Agric Food Chem. 2004 Apr 21:52(8):2358-65.
29. Carluccio MA, Sicuella L, Ancora MA et al. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thrmob Vasc Biol. 2003 Apr 1;23(4):622-9.
30. Paiva-Martins F, Gordon MH, Gameiro P. Activity and location of olive oil phenolic antioxidants in liposomes. Chem Phys Lipids 2003 Jun;124(1):23-36.
31. Visoli F, Galli C. Biological properties of olive oil phenolic antioxidants in liposomes. Chem Phys Lipids 2003 Jun;124(1)23-56.
32. Haban P, Klvanova J, Zidekova E et al. Dietary supplementation with olive oil leads to improved lipoprotein spectrum and lower n-6 PUFAs in elderly subjects. Med Sci Monit. 2004 Apr;10(4):PI49-54.
33. Vissers MN, Zock PL, Katan MB. Bioavailability and antioxidant effects of olive oil phenols in humans--a review. Eur J Clin Nutr. 2004 June;58(6):955-65.
34. Parker RS, Sontag TJ. Cytochrome P-450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin e status. J Biol Chem. 2002 Jul 12;277(28):25290-6.
35. Meier R, Tomizaki T, Schulze-Briese C eta l. The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. J Mol Bol 2003 Aug 15;331(3)725-34.
36. Ikeda S, Kagaya M, Kobayashi K et al. Dietary sesame lignans decrease lipid peroxidatoin in rats fed docosahexaenoic acid. J Nutri Sci. Vitaminol (Tokyo), 2003 Aug;49(4):2707-6.
37. Kang MH, Naito M, Sakai K et al. Mode of action of sesame lignans in protecting low-density lipoprotein against oxidative damage in vitro. Life Sci. 2000;66(2):161-71.
38. Kang MH, Naito M, Tsujihara N et al. Sesamolin inhibits lipid peroxidation in rat liver and kidney. J Nutr. 1998 Jun;128(6):1018-22.
39. Christen S, Woodall AA, Shigenaga MK et al. Gamma-tocopherol traps mutagenic electrophiles such as NO(X) complements alpha-tocopherol: physiological implications. Proc Natl Acad Sci. USA 1997 Apr;94(7):3217-22.
40. Crawford V, Scheckenbach R, Preuss HG. effects of niacin-bound chromium supplementation on body composition of overweight African-American women. Diabetes Obes Metab. 1999 Nov;1(6):331-7.
41. Grant KE, Chandler RM, Castel AL et al. Chromium and exercise training: Effect on obese women. Med Science Sports Exer. 1997;29:992-8.

Dosage and Use

  • Fourteen capsules per day in divided doses with meals.

  • The niacin in this product may cause flushing (a feeling of warmth and reddening of the skin). This effect is temporary and harmless.

  • Refrigeration is recommended.

Caution

    This product should not be used by individuals who have an allergy to sesame.

Warnings

  • Keep out of reach of children.

  • Do not exceed recommended dose.

  • If you have a bad reaction to this product, discontinue use.

  • When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

 

 Warning: These products are not intended to diagnose, treat, cure or prevent any disease. Please consult with a healthcare professional before starting any diet or exercise program. Some of these products are not recommended for individuals under the age of 18. 

This page was last modified on Friday March 05, 2010